Provisional Program


Workshop: “Folding Chromatin in Three dimensions”

04 February 2016 – Center for Genomic Science of IIT@SEMM

Conference Room, IFOM/IEO Campus, via Adamello 16, 20139 – Milan

When What Speaker
8:30-11:00 Session I - Chair: Bruno Amati


Arrival & Registration  
09:15-09:30 Welcome Address

Bruno Amati

IIT and IEO,
Milan, IT

09:30-10:00 The functional 3D genome and novel chromatin conformation applications

Wouter De Laat

Hubrecht Institute,
Utrecht, NL

10:00-10:30 Genome-wide suppression of non-coding transcription in mammals

Gioacchino Natoli

Milan, IT

10:30-11:00 Entrepreneurship – Diagenode’s history

Renaud Schoemans

Seraing, BE

11:00-11:30 Coffee break
11:30-13:00 Session II - Chair: Bruno Amati
11:30-12:00 Chromosome-wide regulation of the X chromosome for dosage compensation

Peter Becker

LMU – Adolf Butenandt Institute,
München, DE

12:00-12:30 Cohesin and gene regulation

Matthias Merkenschlager

Imperial College
London, UK

12:30-13:00 Cistromic and long-range interactions of lineage- and signal specific transcription factors integrate macrophage specification and control lipid signaling

László Nagy

Debrecen, HU

13:00-14:00 Lunch break
14:00-15:30 Session III - Chair: Babis Spilianakis
14:00-14:30 Control of Cell Identity by Polycomb Group Proteins

Diego Pasini

Milan, IT

14:30-15:00 Unraveling chromatin and gene regulation through thousands of synthetically designed regulatory sequences

Eran Segal

Weizmann Institute of Science,
Rehovot, IL

15:00-15:30 Locating and counting nucleosomes

Marco E. Bianchi

San Raffaele University,
Milan, IT

15:30-16:00 Coffee break
16:00-18:10 Session IV - Chair: Babis Spilianakis
16:00-16:30 Circadian chromatin transitions in the 3D nuclear architecture

Anita Gӧndӧr

Karolinska Institutet,
Stockholm, SE

16:30-17:00 Nucleotide Excision Repair and its functional Role in Development and Disease

George Garinis

University of Crete & IMBB, FORTH,
Heraklion, GR

17:00-17:30 The role of DNA damage-induced RNAs in the control of genome stability

Fabrizio d’Adda di Fagagna

Milan and Pavia, IT

17:30-18:00 Spatial proximity of homologous alleles and long noncoding RNAs regulate a switch in allelic gene expression

Babis Spilianakis

University of Crete & IMBB, FORTH,
Heraklion, GR

18:00-18:10 Concluding remarks Babis Spilianakis



March 17. 2017 – Nobel Forum, Karolinska Institutet

When What Speaker

Session I - Phenotypic Plasticity and Tumor Evolution

Chair: Bruno Amati, Italian Institute of Technology (IIT) & European Institute of Oncology (IEO)


Arrival & Registration  
08:50-09:00 Welcome Address

Anita Göndör

 09:00-09:40 Keynote lecture, "Epigenomic Stochasticity in Tumor Evolution"

Andrew P. Feinberg

Johns Hopkins University School of Medicine,

9:40-10:15 Alterations of the Polycomb machinery in cancers

Rafaël Margueron

Institut Curie,

10:15-10:50 Epigenetic plasticity and cancer: lessons learned from SIRT6

Raul Mostoslavsky

MGH Cancer Center, Harvard Medical School,

10:50-11:15 Coffee break

Session II - Transcriptional regulation and MYC

Chair: Wendy Bickmore, University of Edinburgh, IGMM

11:15-11:50 Transcriptional programs and therapeutic targets in Myc-driven tumors

Bruno Amati

Italian Institute of Technology (IIT) & European Institute of Oncology (IEO),

11:50-12:25 New perspectives on the transcriptional regulation of MYC in 3D

Rolf Ohlsson

Karolinska Institutet

12.25-13.45 Lunch break

Session III - Chromatin and genome maintenance

Chair: Terumi Kohwi-Shigematsu, UCSF, School of Dentistry, San Fransisco

13:45-14:20 Common Fragile Site replication: a race against time

Michelle Debatisse

Institut Curie, 

14:20-14:55 Genome Architecture Mapping, an orthogonal approach to map chromatin contacts

Ana Pombo

Humboldt University

14:55-15:30 Nuclear organization in genome maintenance

Evi Soutoglou

Institut de Genetique De Biologie Moleculaire et Celluraire (IGBMC) ,

15:30-15:55 Coffee break

Session IV - Epigenetic targets in diagnosis and therapy

Chair: Maria Berdasco Menendez, Hospital Duran i Reynals, Barcelona

15:55-16:30 Epigenetic Targets in Cancer

Kristian Helin

University of Copenhagen

16:30-17:05 Identification of ligand insensitive bookmarking and architectural functions for nuclear hormone receptors in gene expression regulation

László Nagy

University of Debrecen and UD-GenoMed

17:05-17:40 Modifications of RNA in Transcription and Cancer

Tony Kouzarides

The Gurdon Institute,
University of Cambridge

17.40-17.45 Concluding remarks